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Nathan Petrelli and Mr. Linderman discuss Nathan's future and the prophesied explosion. Linderman explains how he is looking to provide humanity with a "pathway to a more permanent peace." Nathan is horrified to learn that this plan involves using his brother Peter as the catalyst for an explosion that will kill a majority of the people in New York City. Linderman states that, even if half the population of New York City was killed in the blast, it would only represent less than .07% of the world's population, an acceptable loss. He also reveals that he has the power to heal others and that he used to be part of a group of heroes, but he grew weary of saving the world "one life at a time" and instead plans to help the world save itself, with Nathan emerging as the unifying voice after the tragedy. Among the paintings Linderman shows to Nathan, one is where Nathan is standing in the Oval Office.

Linderman shows Nathan his prediction as a future president.

Claire Bennet is still in shock from having learned that Angela Petrelli is not only her grandmother, but has known of her existence all along, even when Nathan thought she was dead after the fire. Angela strongly implies that she was a former hero and has powers. She informs Claire that it is not safe for her to be in New York City right now. She tells Claire that the two of them will soon be leaving for Paris until after the events that are coming play themselves out.

Peter manages to halt Sylar's telekinetic attack, healing his forehead and flinging Sylar across the room with telekinesis. Mohinder, who is pinned to the ceiling by Sylar's telekinesis, falls to the floor when Sylar's concentration is broken. Sylar is soon back on his feet and about to attack Peter when Peter becomes invisible, to Sylar's surprise. Sylar uses his telekinesis to fling shattered glass in all directions across the room. One of the shards stops in mid-air, dripping blood. Peter reappears, and we see that it is embedded in the back of his skull. He falls to the floor, lifeless.

In desperation, Mohinder pushes Sylar against a wall with the rolling bulletin board, knocking him unconscious and giving Mohinder time to escape with Peter. Later, Sylar revives to find that Mohinder has destroyed the notes on the bulletin board and the computer containing the list of "heroes." Sylar is enraged, until he finds a torn inside cover of 9th Wonders! with Isaac Mendez's name and address on it.

Mohinder arrives at Angela Petrelli's house, informing her that Peter is dead. He lays Peter's corpse on a chaise longue and Nathan arrives and immediately comes to Peter's side, clutching him and weeping. Nathan says "He wasn't supposed to die this way.", referencing the atomic prediction. Claire comes down the stairs to find Peter lying in the lounge, dead. She finds the glass shard and pulls it out of his head, allowing Peter to revive instantaneously.

Isaac, meanwhile, has finished the next issue of 9th Wonders! and is meeting with his usual courier, who is an avid fan of the series. Isaac tells the courier that the new issue, in which Hiro travels to the future, is the final one, and gives the man his sketchbook as a gift. The courier leaves, and Isaac is left gazing at the painting of his own death.

Nathan and Claire finally meet. Nathan urges her to accompany his mother to Paris for a week, because of the impending election. Claire deduces Nathan is talking about her as his illegitimate daughter; Nathan, however, seems to be viewing Linderman's plan with a less moralistic eye, especially since Linderman gave Nathan Isaac's painting of Nathan standing in the Oval Office. Claire finally agrees to go, and father and daughter embrace warmly.

Candice Wilmer assumes the form of Claire in an attempt to get information from Mr. Bennet. Bennet sees through the ruse, and tells Thompson that he cannot tell them what he does not know: the location of Claire. Thompson informs him that they are merely waiting for orders before they can kill Bennet. Once Bennet is alone, he telepathically tells Matt Parkman, locked in a nearby cell, how to escape by attacking a guard. Bennet orders him to release Ted Sprague and have Sprague generate an electromagnetic pulse to shut down all power in the facility. The plan succeeds, and Parkman and Sprague release Bennet and escape from the facility. Later, at the Burnt Toast Diner, Bennet explains that the only way to stop Thompson is to get to New York to shut down the tracking device that tracks heroes tagged with the neck tattoo. Sprague agrees, and Matt reluctantly agrees to join them.

Jessica Sanders finally meets Linderman face-to-face, and he requests the opportunity to meet Micah because he wishes to use his abilities. Jessica refuses Linderman's request, stating that Micah is not part of their deal. Candice impersonates Jessica/Nikki and picks up Micah early from school and tricks Micah into going with Linderman. Linderman asks Micah if he would like to save the world. As Linderman leaves with Micah, the real Jessica pulls up to the front of the house as Candice leaves, having morphed back to her "normal" form.

Mohinder meets Thompson back at his apartment, wanting revenge on Sylar for killing his father and Peter. Thompson asks Mohinder to join The Company so he can get his revenge.

Isaac Mendez and Sylar finally encounter each other, with a painting of Sylar killing Isaac in the background. When Sylar wonders why Isaac isn't afraid, Isaac calmly explains that he has accepted his fate and that Sylar will be stopped in the future. Sylar asks Isaac to show him this "future" with a painting, but Isaac states that the paintings are gone. Sylar flings him to the ground and impales Isaac's wrists and ankles with paint brushes. With his last words, Isaac says that he has made many wrong decisions in his life, but through this final act he " finally gets to be a hero."

What Sylar paints after taking Isaac's ability.

Sylar kills Isaac and absorbs his precognitive power, as he is later seen painting a grotesque picture of himself in the Oval Office, similar to the one of Nathan Petrelli painted by Isaac shown earlier in the episode.

Hiro and Ando find themselves on top of the Deveaux Building, five years into the future, in the midst of a devastated New York City, wondering about their mistakes and what they must have done wrong for the explosion to take place. Remembering that Isaac told them that the "brain man" was in jail, Hiro thinks that Isaac might still be alive and know what to do. They enter his studio where they find newspaper clippings strung together by string all over the apartment, which Hiro supposes is a timeline of the events of everything that happened. The episode ends with Hiro coming face-to-face with his future self.